Chimeron Bio Careers
Principal Scientist/Associate Director/Director

This position is a highly influential position in the Company, and is a combination of managing scientists and experiments, collaborating with external partners and hands-on laboratory work. The candidate will effectively lead preclinical development projects with minimal supervision, lead and manage interactions with CROs, academic collaborators, consultants and colleagues within the Company, while contributing to the R&D strategy. The candidate will also help establish a team of scientists to help advance the Company‚Äôs technology and pipeline.

Responsibilities and Expectations are as follows:

  • Design, execute and conduct studies, both GMP and non-GMP towards inclusion in IND. The role involves leading target validation, PK/PD and mechanism of action studies across multiple therapeutic areas.
  • Conceive, communicate and execute multi-disciplinary research strategies that will encompass target validation, biomarker identification and early development of novel therapeutics.
  • Help recruit, lead and manage a team of Ph.D. and non-Ph.D. lab scientists.
  • Develop a cohesive and nurturing team environment, based on respect, individual strengths and empowerment. 
  • Work alongside senior leaders of the Company to deliver set goals and objectives.
  • Be the point person for external collaborators and CROs with the aim to advance drug discovery programs.
  • Superior attention to detail when recording and analyzing data.
  • Maintain well-organized laboratory notebooks as per Company guidelines.
  • Participate in the production and quality control of RNA nanoparticles.
  • Develop and improve methods for formulation. Assist in the transfer of production protocols to cGMP facility.
  • Assist in grant writing and preparation of presentations to stakeholders.
  • Stay current with respect to new and relevant technologies through reading scientific literature, etc.

The successful candidate must have the ability to accomplish the above tasks in a collaborative manner, with minimal supervision.

Candidate Qualifications:

  • Ph.D. in Cell and Molecular Biology, Virology or related scientific disciplines with 3-5 years of industry experience in preclinical drug development obtained at a Pharmaceutical, Biotech or CRO. Master of Science with greater than 8 years of Pharmaceutical, Biotech or CRO experience.
  • Demonstrated expertise in target validation, drug discovery and translational research across multiple indications.
  • Held a Leadership role or participated in pre-clinical programs from target validation to candidate selection and beyond.
  • Performed due diligence on new technologies and targets. Presented to stakeholders and obtained funding for advancing ideas.
  • Demonstrated ability to multitask, managed multiple stakeholder interactions in a matrix team environment.
  • Possess strong expertise in in-vitro and in-vivo assay design and development, data interpretation and analysis.
  • Proficient in mammalian tissue culture, Flow Cytometry, ELISA, Immunofluorescence Microscopy, molecular cloning, and standard molecular biology and protein biochemistry techniques. Hands-on experience with viral expression and formulation production is a plus.
  • Experience in leading teams and training scientists.
  • Possess excellent verbal and written communication skills.
  • Ph.D. in Cell and Molecular Biology, Virology or related scientific disciplines with 3-5 years of industry experience in preclinical drug development obtained at a Pharmaceutical, Biotech or CRO. Master of Science with greater than 8 years of Pharmaceutical, Biotech or CRO experience.
  • Demonstrated expertise in target validation, drug discovery and translational research across multiple indications.
  • Held a Leadership role or participated in pre-clinical programs from target validation to candidate selection and beyond.
  • Performed due diligence on new technologies and targets. Presented to stakeholders and obtained funding for advancing ideas.
  • Demonstrated ability to multitask, managed multiple stakeholder interactions in a matrix team environment.
  • Possess strong expertise in in-vitro and in-vivo assay design and development, data interpretation and analysis.
  • Proficient in mammalian tissue culture, Flow Cytometry, ELISA, Immunofluorescence Microscopy, molecular cloning, and standard molecular biology and protein biochemistry techniques. Hands-on experience with viral expression and formulation production is a plus.
  • Experience in leading teams and training scientists.
  • Possess excellent verbal and written communication skills.

Chimeron Bio is committed to providing a motivating work environment while simultaneously emphasizing a healthy work-life balance. We offer competitive compensation and benefits to foster professional and personal leadership and growth. Benefits include a competitive base pay, bonuses based on milestone targeted performance, stock options, paid employee medical, vision and dental insurance, PTO and other fringe benefits.

Qualified candidates are encouraged to click below to apply or send their resumes or CV to careers@chimeron.com with the Job Title in the subject heading.

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Explore Our Pipeline of saRNA-Based Medicines

See how Chimeron Bio is applying ChaESAR to develop therapeutics in our key focus areas of oncology, liver, and kidney-related genetic disorders and infectious diseases.

View Pipeline